Chemical Intermediate Itraconazole Powder CAS 84625-61-6 Antifungal Itraconazole

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Itraconazole
• CAS: 84625-61-6
• Mf: C35h38cl2n8o4
• Sample: Available
• MOQ: 1kg
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

Itraconazole is a new generation of highly effective broad-spectrum anti-fungal triazole that binds to fungal cytochrome P450 isoenzymes and inhibits ergosterol synthesis. The goods on the dermatophytes, Candida, Cryptococcusneoformans,Pityrosporum,Aspergillus, histoplasmosis, Paracoccidioides sporogenes, Spirulina conidia, colored fungi, Cladosporium , Dermatitis germs andother infections effective.

 

 

Product Name	Itraconazole
Appearance	White Powder
CAS NO.	84625-61-6
Molecular Formula	C35H38Cl2N8O4
Storage	Keep in a cool, dry, dark location

 

1. Antifungal Treatment: Itraconazole is primarily used for the treatment of various fungal infections, including but not limited to systemic mycoses, dermatomycoses, and onychomycosis.

2. Immunocompromised Patients: It is prescribed for immunocompromised individuals, such as those with HIV/AIDS or undergoing chemotherapy, who are more susceptible to fungal infections.

3. Preventive Therapy: Itraconazole can also be employed as a prophylactic agent to prevent fungal infections in high-risk individuals or in settings where exposure to fungi is anticipated.

1. Inhibition of Fungal Cell Membrane Synthesis: By inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, itraconazole disrupts membrane integrity and function, leading to fungal cell death.

2. Broad-Spectrum Activity: Its mechanism of action enables itraconazole to exhibit broad-spectrum antifungal activity against a wide range of fungal species, including yeasts, molds, and dermatophytes.

3. Oral Bioavailability: Administered orally, itraconazole achieves good bioavailability, allowing it to reach therapeutic concentrations in the bloodstream and distribute throughout the body, making it effective against systemic and deep-seated fungal infections.

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