Factory 99% Atorvastatin Calcium Powder CAS 134523-03-8 Atorvastatin Calcium

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A271
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Atorvastatin Calcium
• CAS: 134523-03-8
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 100g
• Function: Hyperlipidemia Treatment
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Atorvastatin Calcium
Appearance	White Powder
CAS NO.	134523-03-8
Molecular Formula	C66H68CaF2N4O10
Storage	Keep in a cool, dry, dark location

 

Atorvastatin Calcium is a synthetic lipid-lowering agent belonging to the statin class of drugs. It acts as a selective and competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme responsible for the conversion of HMG-CoA to mevalonate, a key step in cholesterol biosynthesis.

 

 

1. Hyperlipidemia Management: Atorvastatin Calcium is primarily prescribed for the treatment of hyperlipidemia, including primary hypercholesterolemia, mixed dyslipidemia, and hypertriglyceridemia.
2. Cardiovascular Disease Prevention: By lowering LDL-C (low-density lipoprotein cholesterol) and triglyceride levels, and increasing HDL-C (high-density lipoprotein cholesterol) levels, Atorvastatin Calcium helps reduce the risk of cardiovascular diseases, such as heart attacks and strokes.
3. Combination Therapy: It may also be used in combination with other lipid-lowering therapies or as an adjunct to diet for the reduction of elevated total cholesterol, LDL-C, apolipoprotein B, and triglycerides in patients with primary hypercholesterolemia and mixed dyslipidemia.

1. Cholesterol Synthesis Inhibition: Atorvastatin Calcium inhibits the activity of HMG-CoA reductase, thereby reducing the production of cholesterol in the liver and decreasing the levels of LDL-C in the blood.
2. LDL-C Receptor Upregulation: It also upregulates the expression of LDL receptors on the surface of liver cells, enhancing the uptake of LDL-C from the bloodstream and further reducing its levels.
3. Pleiotropic Effects: Beyond its cholesterol-lowering properties, Atorvastatin Calcium has been shown to exhibit pleiotropic effects, including anti-inflammatory, antioxidant, and endothelial-protective activities, which may contribute to its overall cardiovascular benefits.