Factory 99% Lumefantrine Powder CAS 82186-77-4 Antimalarial Artemether Lumefantrine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A582
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Lumefantrine
• CAS: 82186-77-4
• Appearance: Yellow Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 10g
• Function: Antimalarial
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Lumefantrine
Appearance	Yellow Powder
CAS NO.	82186-77-4
MF	C30H44N2O2
Storage	Keep in a cool, dry, dark location

 

Lumefantrine is an antimalarial drug belonging to the aryl aminoalcohol class of compounds. It is commonly used in combination with artemisinin derivatives for the treatment of uncomplicated malaria caused by Plasmodium falciparum.

 

1. Combination Therapy: Lumefantrine is primarily administered in fixed-dose combination with artemisinin-based drugs, enhancing the efficacy and reducing the risk of resistance development.
2. Malaria Elimination Programs: Due to its long half-life and effectiveness against multidrug-resistant Plasmodium strains, lumefantrine is a key component in malaria elimination programs worldwide.
3. Post-Exposure Prophylaxis: In some regions, lumefantrine is also used as a post-exposure prophylactic measure for individuals at high risk of malaria infection.

1. Parasite Killing: Lumefantrine acts on the malaria parasite by inhibiting its heme detoxification pathway, leading to the accumulation of toxic heme products and eventual parasite death.
2. Schizonticidal Activity: It exhibits schizonticidal activity against Plasmodium species, particularly effective during the erythrocytic phase of the parasite's life cycle.
3. Gametocytocidal Effect: Lumefantrine also has a gametocytocidal effect, reducing the transmission of malaria by killing the sexual stages of the parasite that are responsible for infecting mosquitoes.