Factory 98% Podophyllin Powder Natural Podophyllum Extract CAS 9000-55-9 Podophyllum Resin

• Customization: Available
• Certification: RoHS, BRC, ISO, FDA, HACCP
• Assay Method: HPLC-MS, GPC, HPLC, UV
• Model NO.: C85
• Application Form: Injection, Lotion, Suppository, Paste, Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Aloe Vera Extract
• Name: Podophyllin Resin
• Appearance: Brown Powder
• Assay: 98%
• CAS: 9000-55-9
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 10g
• Transport Package: Foil Bag
• Specification: 98
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Podophyllin Resin
Appearance	Brown Powder
CAS NO.	9000-55-9
Storage	Keep in a cool, dry, dark location

 

Podophyllin resin is a naturally derived cytotoxic resin extracted from the rhizomes of Podophyllum species (e.g., Podophyllum peltatum or Podophyllum emodi). It is a complex mixture containing podophyllotoxin, a lignan with antiproliferative properties, along with other bioactive compounds. Historically used in traditional medicine, this bitter-tasting resin acts as a caustic agent and has been employed topically for its keratolytic and tissue-destructive effects, primarily in dermatological applications.

 

1. Dermatological Treatments:
   • Wart Removal: Applied topically to treat genital warts (condylomata acuminata) and other cutaneous lesions by inducing necrosis of abnormal epithelial tissues.
   • Skin Lesions: Used for localized verrucae, molluscum contagiosum, and certain pre-malignant skin conditions.
2. Oncological Research:
   • Investigated as a precursor for semi-synthetic derivatives (e.g., etoposide, teniposide) in chemotherapy, though its direct use in cancer treatment is limited due to systemic toxicity.
3. Veterinary Medicine:
   • Rarely used to treat papillomatosis in animals, though safer alternatives are now preferred.

1. Cytotoxic and Antimitotic Effects:
   • Inhibits microtubule assembly by binding to tubulin, arresting cells in metaphase of mitosis, and inducing apoptosis in rapidly dividing cells.
2. Keratolytic and Caustic Action:
   • Causes localized necrosis of epidermal tissues, facilitating the removal of hyperkeratotic or warty growths through chemical destruction.
3. Antiviral Potential:
   • Exhibits activity against DNA viruses (e.g., HPV) by disrupting viral replication in infected epithelial cells, though clinical efficacy varies.