Factory 99% Tucatinib Powder CAS 937263-43-9 Chemical Intermediate Tucatinib

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A439
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Tucatinib
• CAS: 937263-43-9
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 10g
• Function: Anti-Inflammatory
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Tucatinib
Appearance	White Powder
CAS NO.	937263-43-9
Molecular Formula	C26H24N8O2
Storage	Keep in a cool, dry, dark location

 

 

 

Tucatinib, with the chemical formula C26H24N8O2, is a highly selective oral small-molecule tyrosine kinase inhibitor targeting HER2.
 

 

 

1. HER2-Positive Breast Cancer Treatment: Tucatinib is primarily used in the treatment of HER2-positive breast cancer, particularly in cases involving brain metastases.
2. Combination Therapy: It is often used in combination with other drugs such as capecitabine and trastuzumab to enhance therapeutic efficacy.
3. Oral Administration: Tucatinib is available in oral film-coated tablet form, making it convenient for patients to administer.

1. HER2 Inhibition: Tucatinib inhibits the kinase activity of HER2, thereby blocking the signal transduction on the cell surface and inhibiting the proliferation and growth of tumor cells.
2. Broad Inhibition: Unlike other HER2 inhibitors, Tucatinib not only acts on HER2-positive cells but also prevents HER2-positive tumors from releasing signal molecules to adjacent tumor cells, avoiding the "seed and soil effect".
3. Blood-Brain Barrier Penetration: Tucatinib can penetrate the blood-brain barrier, making it an effective treatment option for HER2-positive breast cancer patients with brain metastases.