Factory 99% Clomipramine HCl CAS 17321-77-6 Antidepressant Clomipramine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A338
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Clomipramine HCl
• CAS: 17321-77-6
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 100g
• Function: Antidepressant
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Clomipramine HCl
Appearance	White Powder
CAS NO.	17321-77-6
Molecular Formula	C19H24Cl2N2
Storage	Keep in a cool, dry, dark location

 

Clomipramine HCl, also known as Anafranil, is a hydrochloride salt of clomipramine. It is a white to slightly yellow crystalline powder with a specific molecular formula of C19H24Cl2N2 and a molecular weight of 351.313.

 

 

1. Pharmaceutical Ingredient: It is primarily used as an active ingredient in pharmaceutical preparations, particularly in antidepressants.
2. Research Purposes: It is also employed in scientific research to study the mechanisms of depression and obsessive-compulsive disorder (OCD).
3. Chemical Intermediate: Serves as an intermediate in the synthesis of other chemicals or drugs.

1. Antidepressant and Anti-obsessional Effects: It effectively blocks the reuptake of serotonin (5-HT), norepinephrine (NE), and dopamine (DA), thereby increasing their synaptic concentrations and alleviating depressive and obsessive-compulsive symptoms.
2. Neurotransmitter Transporter Blocker: It acts as a selective inhibitor of serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), with Ki values of 0.14 nM, 54 nM, and 3 nM, respectively.
3. Modulation of Neuronal Activity: It has been shown to regulate neuronal autophagic pathways, potentially contributing to its therapeutic effects in various neurological and psychiatric conditions.