Factory 99% Amodiaquine HCl Powder CAS 6398-98-7 Chemical Intermediate Amodiaquine HCl

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A973
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Amodiaquine HCl
• CAS: 6398-98-7
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Amodiaquine HCl
Appearance	White Powder
CAS NO.	6398-98-7
Storage	Keep in a cool, dry, dark location

 

Amodiaquine HCl, also known as amodiaquine hydrochloride, is an antimalarial medication that belongs to the 4-aminoquinoline class of drugs. It is a synthetic derivative of quinine, a naturally occurring compound found in the bark of the cinchona tree. 

 

1. Treatment of Malaria: Amodiaquine HCl is primarily used in the treatment of uncomplicated malaria, particularly in areas where chloroquine resistance is prevalent. It is often combined with other antimalarial drugs to enhance efficacy and reduce the risk of resistance development.

2. Prophylaxis: In some instances, amodiaquine HCl may be used for malaria prophylaxis, especially in travelers visiting malaria-endemic regions. However, its use for this purpose is less common compared to other prophylactic medications due to potential side effects and the need for close monitoring.

3. Combination Therapy: Amodiaquine HCl is frequently used as part of combination therapy for malaria treatment. This approach helps to delay the emergence of drug resistance by targeting the parasite with multiple mechanisms of action simultaneously.

1. Parasiticidal Activity: Amodiaquine HCl exerts its antimalarial effect by killing the malaria parasites within the red blood cells. It disrupts the parasite's metabolic processes, leading to the accumulation of toxic substances that ultimately result in parasite death.

2. Heme Metabolism Inhibition: The drug interferes with the parasite's ability to detoxify heme, a byproduct of hemoglobin digestion. This interference leads to the accumulation of toxic heme species, which contribute to the parasite's demise.

3. Synergistic Effects: When used in combination with other antimalarial agents, amodiaquine HCl can enhance the overall efficacy of treatment. This synergistic effect helps to overcome drug resistance and improve patient outcomes.