| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Mifepristone |
| Appearance | Yellow Powder |
| CAS NO. | 84371-65-3 |
| Molecular Formula | C29H35NO8 |
| Storage | Keep in a cool, dry, dark location |
Mifepristone, also known as RU-486, is a synthetic steroid with potent antiprogestational and glucocorticoid antagonist properties. It is primarily used in medical abortion procedures and for the treatment of certain hormonal disorders.
Medical Abortion: Mifepristone is the primary medication used in combination with misoprostol for medical abortions up to the ninth week of pregnancy. It works by blocking the progesterone receptor, which causes the pregnancy tissue to detach from the uterine wall.
Hormonal Disorders: It is also prescribed for the treatment of Cushing's syndrome, a hormonal disorder characterized by high levels of cortisol, and for the management of endometrial hyperplasia, a condition where the lining of the uterus becomes abnormally thick.
Antiprogestational Effect: Mifepristone blocks the progesterone receptor in the body, which is crucial for maintaining a pregnancy. By disrupting the progesterone signaling, it causes the pregnancy tissue to detach and be expelled from the uterus.
Glucocorticoid Antagonist Effect: In conditions like Cushing's syndrome, mifepristone binds to glucocorticoid receptors without activating them, thereby reducing the effects of excess cortisol in the body.
Endometrial Thinning: By inhibiting the proliferation of endometrial cells, mifepristone helps in reducing the thickness of the uterine lining, making it useful in the management of endometrial hyperplasia.
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