Factory 99% Guanfacine HCl Powder CAS 29110-48-3 Chemical Intermediate Guanfacine HCl

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A895
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Guanfacine HCl
• CAS: 29110-48-3
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Guanfacine HCl
Appearance	White Powder
CAS NO.	29110-48-3
Storage	Keep in a cool, dry, dark location

 

Guanfacine HCl, also known as Guanfacine hydrochloride, is a centrally acting alpha-2A adrenergic receptor agonist. 

 

1. Hypertension Treatment: Guanfacine HCl is primarily used in the treatment of hypertension, particularly in adults. It helps lower blood pressure by acting on the central nervous system.

2. Pediatric Use: It is also indicated for the treatment of attention-deficit/hyperactivity disorder (ADHD) in children and adolescents aged 6 to 17 years. Guanfacine HCl can improve attention, reduce hyperactivity, and enhance impulse control.

3. Adjunctive Therapy: In some cases, Guanfacine HCl may be used as an adjunct to other antihypertensive medications or behavioral therapies for ADHD.

1. Central Nervous System Modulation: Guanfacine HCl acts on the alpha-2A adrenergic receptors in the central nervous system, reducing sympathetic outflow to the peripheral vasculature. This leads to a decrease in peripheral vascular resistance and blood pressure.

2. Attention and Behavior Regulation: In pediatric patients with ADHD, Guanfacine HCl is believed to enhance prefrontal cortical function, improving attention, reducing impulsivity, and increasing inhibitory control.

3. Prolonged Duration of Action: Guanfacine HCl has a relatively long half-life, allowing for once-daily dosing. This contributes to its effectiveness in maintaining blood pressure control and improving ADHD symptoms over an extended period.