Chemical Intermediate Pure Idebenone Powder CAS 58186-27-9 Nootropics Idebenone

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Idebenone
• CAS: 58186-27-9
• Mf: C19h30o5
• Sample: Available
• MOQ: 1kg
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

Idebenone (IDBN) is chemically named 6-(10-hydroxydecyl)-2,3-dimethoxy-5-methylbenzoquinone, which was developed and marketed by Takeda Pharmaceutical Co., Ltd. in 1986 An intelligent stimulant; it has an activating effect on the function of pulling the body.

 

 

 

 

Product Name	Idebenone
CAS Number	58186-27-9
MF	C19H30O5
Molecular Weight	338.44
Purity	99%

 

1. Mitochondrial Antioxidant: Idebenone acts as a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant. It helps reduce oxidative stress by scavenging free radicals and inhibiting lipid peroxidation, thereby protecting the lipid membrane and mitochondria from oxidative damage.
2. ATP Production Enhancer: By interacting with the Electron Transport Chain (ETC) in mitochondria, idebenone facilitates electron transfer to complex III, bypassing complex I. This helps restore cellular energy production (ATP) in damaged mitochondria, improving overall mitochondrial function.
3. Potential Neuroprotective Effects: In the context of LHON and other mitochondrial disorders, idebenone is thought to have neuroprotective effects by reactivating viable-but-inactive retinal ganglion cells (RGCs) and supporting mitochondrial function in affected neurons. This may contribute to improved visual function and possibly slow disease progression.

1. Treatment of Visual Impairment in LHON: Idebenone is indicated for the treatment of visual impairment in adolescent and adult patients with Leber's Hereditary Optic Neuropathy (LHON), a rare mitochondrial disorder that causes acute central vision loss. It is approved for this use by the European Medicines Agency (EMA).
2. Investigational Use: While not currently approved for other conditions, idebenone is being investigated for potential use in other disorders associated with mitochondrial damage, including Alzheimer's disease and other cognitive disorders, due to its ability to reduce oxidative damage and improve ATP production.
3. Nutritional Supplements: Idebenone is also available as a nutritional supplement, marketed in liposomal formulations for enhanced bioavailability and absorption. These supplements are often promoted for brain health and cognitive function, although their efficacy for these purposes has not been fully established by regulatory agencies.

 

Pro-xylane	Potassium azeloyl diglycinate
Ghk-Cu or other Cosmetic peptides	Glutathione
Spermidine	5-deazaflavin
PQQ	Coenzyme Q10
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