| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Hydrochlorothiazide |
| Appearance | White Powder |
| CAS NO. | 58-93-5 |
| Molecular Formula | C7H8ClN3O4S2 |
| Storage | Keep in a cool, dry, dark location |
Hydrochlorothiazide is a diuretic medication belonging to the thiazide class of diuretics. It is a sulfonamide derivative that acts on the kidneys to increase the excretion of salt and water, thereby reducing blood volume and blood pressure.
Edema Management: It is used to treat edema (fluid retention) associated with various conditions such as congestive heart failure, liver cirrhosis, and nephrotic syndrome.
Hypertension Treatment: Hydrochlorothiazide is commonly prescribed for the management of hypertension, either alone or in combination with other antihypertensive agents.
Diagnostic Aid: It can also be used as an aid in diagnostic procedures to differentiate renal from non-renal causes of edema.
Diuretic Effect: By inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubule, hydrochlorothiazide increases the excretion of sodium, chloride, and water, leading to a reduction in extracellular fluid volume and edema.
Antihypertensive Effect: The diuretic action of hydrochlorothiazide results in a decrease in blood volume and plasma volume, which in turn leads to a reduction in cardiac output and peripheral vascular resistance, thereby lowering blood pressure.
Renal Effects: In addition to its diuretic and antihypertensive effects, hydrochlorothiazide may also affect renal function by altering the excretion of other electrolytes such as potassium, magnesium, and calcium.
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