Factory Supply 99% Mildronate Powder CAS 76144-81-5 Met-88/Mildronate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A7
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Mildronate
• CAS: 76144-81-5
• Appearance: White Powder
• Grade: Pharmaceutical Grade
• Assay: 99%
• Sample: Available
• OEM: Available
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Mildronate
Appearance	white powder
Purity	99%
CAS No	76144-81-5
Molecular Formula	C6H14N2O2

Mildronate, is a cardiovascular protective agent that belongs to a class of metabolic modulators. It exhibits a unique mechanism of action, primarily focused on enhancing myocardial energy metabolism and promoting cardiac resilience.

1. Cardiovascular Protection: Mildronate is primarily used as a cardioprotective agent to improve myocardial energy metabolism and enhance the tolerance of the heart to ischemia and/or reperfusion injury.
2. Sports Performance Enhancement (Controversial): While not officially approved for this purpose, Mildronate has been associated with sports doping due to its potential to improve endurance and recovery in athletes. However, its use in sports is banned by several international sporting organizations.
3. Neurological Conditions (Investigational): Research is ongoing to explore the potential of Mildronate in treating neurological conditions, such as cerebrovascular disorders and neurodegenerative diseases, due to its ability to modulate energy metabolism.

1. Modulates Energy Metabolism: Mildronate modulates myocardial energy metabolism by inducing the redirection of long-chain fatty acid metabolism from mitochondria to peroxisomes, thereby improving cardiac function during ischemia.
2. Carnitine-Lowering Effect: It exerts a carnitine-lowering effect, which is believed to contribute to its cardioprotective properties by altering the balance of carnitine and its metabolites in the heart.
3. Inhibits Transporters: Mildronate competitively inhibits the carnitine/organic cation transporter BBOX1 and the organic cation transporter OCTN2, which are involved in the transport of carnitine and other organic cations across cellular membranes. This inhibition may play a role in its cardioprotective and metabolic modulating effects.