Factory 99% Slu-PP-332 Powder CAS 303760-60-3 Chemical Intermediate Slu-PP-332

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A977
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Slu-PP-332
• CAS: 303760-60-3
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	SLU-PP-332
Appearance	White Powder
CAS NO.	303760-60-3
Storage	Keep in a cool, dry, dark location

 

SLU-PP-332 (4-hydroxy-N'-(2-naphthylmethylene)benzohydrazide; CAS: 303760-60-3) is a synthetic compound classified as an estrogen-related receptor (ERR) agonist. It exhibits high affinity for ERRα, ERRβ, and ERRγ subtypes, with EC50 values of 98 nM, 230 nM, and 430 nM, respectively. This compound modulates mitochondrial function and cellular metabolism by activating ERR signaling pathways.

 

1. Metabolic Disease Research: SLU-PP-332 is used to investigate ERR-mediated metabolic pathways, particularly in skeletal muscle and adipose tissue, to understand energy homeostasis and sensitivity.
2. Muscle Function Enhancement: It is explored for potential therapeutic applications in sarcopenia and muscle wasting disorders, as it promotes mitochondrial biogenesis and oxidative fiber differentiation (e.g., IIa-type fibers).
3. Aging-Related Studies: SLU-PP-332 is utilized to model mitochondrial dysfunction in aging, offering insights into age-related metabolic decline and potential interventions.

1. Mitochondrial Biogenesis: SLU-PP-332 stimulates mitochondrial proliferation and oxidative phosphorylation, enhancing cellular energy production in skeletal muscle cells.
2. Enhanced Cellular Respiration: By activating ERR signaling, it increases oxygen consumption rate (OCR) and ATP synthesis, improving metabolic efficiency.
3. Oxidative Fiber Differentiation: The compound promotes the transition of muscle fibers toward oxidative phenotypes, which are more resistant to fatigue and beneficial for endurance performance.