Factory 99% Pirenzepine HCl Powder CAS 29868-97-1 Chemical Intermediate Pirenzepine HCl

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A902
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Pirenzepine HCl
• CAS: 29868-97-1
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Pirenzepine HCl
Appearance	White Powder
CAS NO.	29868-97-1
Storage	Keep in a cool, dry, dark location

 

Pirenzepine HCl, also known as Pirenzepine Dihydrochloride, is a selective M1 muscarinic receptor antagonist. It is a pharmaceutical compound that inhibits the action of acetylcholine at M1 muscarinic receptors, primarily found in the central nervous system and parasympathetic nervous system.

 

1. Gastrointestinal Disorders: Pirenzepine HCl is primarily used in the treatment of gastrointestinal disorders, such as peptic ulcer disease, gastric hyperacidity, and gastroesophageal reflux disease. It helps to reduce gastric acid secretion and improve symptoms associated with these conditions.

2. Adjuvant Therapy: It may also be used as an adjuvant therapy in combination with other medications to enhance the treatment effect in certain gastrointestinal disorders.

3. Research Purposes: Due to its specific pharmacological properties, Pirenzepine HCl is also used in research to study the role of muscarinic receptors in various physiological and pathological processes.

1. Antimuscarinic Activity: Pirenzepine HCl competitively blocks muscarinic receptors, particularly the M1 subtype, which are involved in the regulation of gastric acid secretion. By inhibiting these receptors, it reduces gastric acid output and protects the gastric mucosa from acid-induced damage.

2. Reduced Side Effects: Unlike non-selective muscarinic receptor antagonists, Pirenzepine HCl has a lower affinity for M2 and M3 receptors, which are responsible for many of the undesirable side effects associated with anticholinergic drugs. This selectivity allows for a more targeted therapeutic effect with fewer side effects.

3. Central Nervous System Effects: Although Pirenzepine HCl does not readily cross the blood-brain barrier, it has been shown to have some central nervous system effects at higher doses. These effects include impairment of memory and learning, which underscores the importance of using the lowest effective dose to minimize side effects.