Chemical Intermediate Anti-Cancer Raw Material Abemaciclib Powder CAS 1231929-97-7 Abemaciclib

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Abemaciclib
• CAS: 1231929-97-7
• Mf: C27h32f2n8
• Sample: Available
• MOQ: 1kg
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

 

What is Abemaciclib?
 

Product name: LY2835219; Abemaciclib; Bemaciclib
CAS No.: 1231929-97-7
MF: C27H32F2N8
MW:  506.5933864
Appearance: White powder
Standard: 99%min.
Lead time: Immediate delivery
Packing: 1kg/Al-foiled bag

 

 

 

 

 

 

 

 

Product Name	High Quality Pharmaceutical Anti-Cancer Raw Material Abemaciclib Powder CAS 1231929-97-7 Abemaciclib
Appearance	white powder
CAS	1231929-97-7
Assay	99%
Keywords	Abemaciclib;Abemaciclib Powder;Raw Material Abemaciclib
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

1. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers.

   Abemaciclib is a CD4/6 kinase inhibitor. This type of kinase is activated by connecting D-cyclin. In breast cancer cell lines that are estrogen receptor positive (HR+), cyclin D1 and CD4/ 6 It can bind to phosphorylation of retinoblastoma protein (Rb), cell cycle progression and cell proliferation. In vitro, continuous exposure to Abemaciclib inhibits Rb phosphorylation and prevents entry from G1 into the S phase of the cell cycle, leading to cell senescence and apoptosis. In breast cancer xenotransplantation models, Abemaciclib monotherapy or combined with can be administered continuously every day to shrink tumors.

1. Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers.

 

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PQQ	Coenzyme Q10
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