Factory 99% Estrone Powder CAS 53-16-7 Chemical Intermediate Estrone

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A982
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Estrone
• CAS: 53-16-7
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Estrone
Appearance	White Powder
CAS NO.	53-16-7
Storage	Keep in a cool, dry, dark location

 

Estrone (E1) is a naturally occurring estrogenic steroid hormone with the chemical formula C18H22O2 and a molecular weight of 270.37 g/mol. It is one of the three primary estrogens (alongside estradiol and estriol) and is primarily produced in the ovaries (premenopausal women) and peripheral tissues (postmenopausal women) via aromatization of androgens. Estrone is weaker than estradiol but remains biologically active, playing a critical role in estrogenic signaling.

 

1. Hormone Replacement Therapy (HRT): Administered to postmenopausal women to alleviate menopausal symptoms (e.g., hot flashes, vaginal dryness) and reduce the risk of osteoporosis.
2. Oncology: Used in treating estrogen receptor-positive breast cancer in postmenopausal patients, leveraging its estrogenic effects to inhibit tumor growth.
3. Diagnostic Testing: Employed as a biomarker in serum/urine assays to assess estrogen metabolism disorders (e.g., polycystic ovary syndrome, aromatase deficiency).

1. Endocrine Regulation: Binds to estrogen receptors (ERα/ERβ) to modulate gene transcription, influencing reproductive, skeletal, and cardiovascular systems.
2. Metabolic Effects: Enhances hepatic synthesis of sex hormone-binding globulin (SHBG) and promotes lipid redistribution (e.g., increased HDL cholesterol).
3. Tissue-Specific Actions: Supports vaginal epithelial health, maintains bone density, and regulates uterine endometrial growth (via cyclical proliferation/shedding).