| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Benazepril Hydrochloride |
| Appearance | White Powder |
| CAS NO. | 86541-74-4 |
| Molecular Formula | C24h29cln2o5 |
| Storage | Keep in a cool, dry, dark location |
Benazepril hydrochloride, a prodrug of benazeprilat, is a long-acting angiotensionconverting enzyme (ACE) inhibitor useful in the treatment of essential hypertension. In healthy humans, it was well tolerated and showed no phmacokinetic interactions with chlorthalidone, cimetidine, or naproxen. Benazepril hydrochloride is under investigation as a cardiostirnulant.
Hypertension Management: It is primarily used for the treatment of hypertension (high blood pressure) in adults, helping to lower blood pressure levels and reduce the risk of cardiovascular complications.
Heart Failure Treatment: In addition to its blood pressure-lowering effects, benazepril hydrochloride can be prescribed for patients with heart failure, improving cardiac function and symptoms associated with the condition.
Renal Protection: By reducing blood pressure, benazepril can also slow the progression of renal (kidney) disease, particularly in patients with diabetes or hypertension-related kidney damage.
ACE Inhibition: The primary function of benazepril hydrochloride is to inhibit angiotensin-converting enzyme (ACE), an enzyme that promotes the production of angiotensin II, a potent vasoconstrictor (blood vessel-narrowing) hormone.
Vasodilation: By inhibiting ACE, benazepril reduces angiotensin II levels, leading to vasodilation (dilation of blood vessels), which in turn decreases blood pressure and improves blood flow throughout the body.
Aldosterone Reduction: ACE inhibition also leads to decreased production of aldosterone, a hormone that regulates sodium and water retention in the body. This helps the body excrete excess sodium and water, further contributing to blood pressure reduction and fluid balance.
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