Factory 99% Rosiglitazone Powder CAS 122320-73-4 Rosiglitazone

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A355
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Rosiglitazone
• CAS: 122320-73-4
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 100g
• Function: Diabetes Treatment
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Rosiglitazone
Appearance	White Powder
CAS NO.	122320-73-4
Molecular Formula	C18H19N3O3S
Storage	Keep in a cool, dry, dark location

 

Rosiglitazone is a thiazolidinedione (TZD) class drug that acts as a potent agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). PPARγ is a member of the nuclear receptor superfamily, primarily expressed in adipose tissue, and regulates gene expression in response to ligand binding.

 

 

1. Type 2 Diabetes Treatment: Rosiglitazone is primarily used to treat type 2 diabetes mellitus by improving insulin sensitivity, thereby enhancing the utilization of glucose by cells and lowering blood glucose levels.
2. Insulin Sensitizer: It is used as an insulin sensitizer to reduce insulin resistance and improve glycemic control in patients with diabetes.
3. Research and Experimental Use: Rosiglitazone is also used in research settings to study the effects of PPARγ activation on various biological processes, including adipocyte differentiation, glucose and lipid metabolism, and inflammation.

1. Activation of PPARγ: Rosiglitazone binds to and activates PPARγ, leading to the transcription of genes involved in adipocyte differentiation, glucose metabolism, and lipid storage.
2. Improvement of Insulin Sensitivity: By activating PPARγ, rosiglitazone increases the expression of genes that enhance insulin sensitivity, allowing cells to better respond to insulin and utilize glucose.
3. Regulation of Glucose and Lipid Metabolism: Rosiglitazone also affects the regulation of glucose and lipid metabolism, contributing to the overall management of blood glucose levels and lipid profiles in patients with diabetes.