Factory 99% Setipiprant CAS 866460-33-5 Chemical Intermediate Anti Hair Loss Setipiprant

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A418
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Setipiprant
• CAS: 866460-33-5
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 10g
• Function: Anti Hair Loss
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Setipiprant
Appearance	White Powder
CAS NO.	866460-33-5
Molecular Formula	C24H19FN2O3
Storage	Keep in a cool, dry, dark location

 

Setipiprant is a chemical compound with the molecular formula C24H19FN2O3. It is known as a selective and orally active antagonist of the chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), which is a G protein-coupled receptor for prostaglandin D2 (PGD2).

 

 

1. Pharmaceutical Research and Development: Setipiprant is primarily used in pharmaceutical research as a tool compound to investigate the role of CRTH2 in various physiological and pathological processes.
2. Potential Therapeutic Agent: Due to its selective antagonism of CRTH2, Setipiprant has been explored as a potential therapeutic agent for allergic and inflammatory diseases, such as asthma and atopic dermatitis, although further clinical development may be required to confirm its efficacy and safety.
3. Scientific Research: It is also employed in scientific studies to elucidate the signaling pathways and biological functions of CRTH2 in immune cells and other tissues.

1. CRTH2 Antagonism: Setipiprant functions by binding to and inhibiting the activity of CRTH2, thereby modulating the downstream signaling pathways activated by PGD2.
2. Anti-inflammatory Effects: By blocking CRTH2, Setipiprant may exhibit anti-inflammatory effects by reducing the recruitment and activation of immune cells, such as Th2 cells and eosinophils, to sites of inflammation.
3. Potential for New Therapeutic Indications: Recent research suggests that Setipiprant may also have potential therapeutic indications in other diseases, such as male pattern baldness, where CRTH2 has been implicated in the pathological process. However, further investigation is needed to confirm these findings and explore the feasibility of Setipiprant as a treatment option.