| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Sodium Dichloroacetate |
| Appearance | White Powder |
| CAS NO. | 2156-56-1 |
| Molecular Formula | C2H2Cl2NaO2 |
| Storage | Keep in a cool, dry, dark location |
Sodium Dichloroacetate, with the molecular formula C2H2Cl2NaO2, is an organic compound that acts as a metabolic modulator. It is a salt derived from dichloroacetic and is known for its ability to inhibit the enzyme pyruvate dehydrogenase kinase (PDK), thereby affecting cellular energy metabolism.
Medical Research and Treatment: SDCA has been investigated for potential therapeutic applications in various medical conditions, including cancer, metabolic disorders, and neurological diseases.
Biochemical Studies: Due to its ability to modulate cellular metabolism, SDCA is also used in biochemical studies to investigate the role of metabolism in disease processes.
Industrial Applications: Although less common, SDCA may also have industrial applications in the production of certain chemicals or as a raw material in the manufacture of other products.
Metabolic Modulation: By inhibiting PDK, SDCA promotes the activation of pyruvate dehydrogenase complex, which is essential for the conversion of pyruvate to acetyl-CoA in the Krebs cycle. This, in turn, enhances oxidative phosphorylation and ATP production, altering cellular energy metabolism.
Anti-Cancer Effects: Research suggests that SDCA may have anti-cancer properties by disrupting the Warburg effect, a metabolic phenomenon observed in many cancer cells where they preferentially use glycolysis for energy production even in the presence of oxygen.
Neuroprotective Effects: Preliminary studies indicate that SDCA may also exhibit neuroprotective effects by reducing oxidative stress and inflammation, potentially beneficial in the treatment of neurological diseases.
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