Factory 99% Indomethacin Powder CAS 53-86-1 Analgesic Chemical Intermediate Indomethacin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A682
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Indomethacin
• CAS: 53-86-1
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Analgesic
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Indomethacin
Appearance	White Powder
CAS NO.	53-86-1
MF	C19H16N2O4
Storage	Keep in a cool, dry, dark location

 

Indomethacin is a medication primarily used for its anti-inflammatory, analgesic, and antipyretic properties. It acts through inhibition of the cyclooxygenase (COX) enzymes, which are involved in the production of inflammatory mediators such as prostaglandins.

 

1. Pain Management: Indomethacin is prescribed for the relief of moderate to severe pain, particularly in inflammatory conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
2. Inflammatory Diseases: It is also used in the treatment of acute gout, bursitis, and tendinitis, where it helps to reduce inflammation and associated pain.
3. Postoperative Care: Indomethacin can be administered postoperatively to reduce the risk of heterotopic ossification, a complication where bone forms outside the skeletal system.

1. COX Inhibition: By inhibiting the activity of the COX enzymes, indomethacin reduces the synthesis of prostaglandins, which are key players in the inflammatory response. This leads to decreased inflammation, pain, and fever.
2. Analgesic Effect: The drug exhibits analgesic properties, providing relief from pain by altering the perception and transmission of nociceptive signals.
3. Antipyretic Action: Indomethacin also has antipyretic effects, reducing body temperature by inhibiting prostaglandin-mediated pathways involved in fever regulation.