| Customization: | Available |
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| CAS No.: | 497-30-3 |
| Formula: | / |
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Description
Ergothioneine(EGT) is an important active substance in human boday.Ergothioneine is obtained by multi fermentation of Hericium Erinaceum & Tricholoma Matsutake.Multi fermentation can increase the yield of L-Ergothioneine,which is a sulfur-containing derivative of the amino acid histidine,a unique stable antioxidant and cytoprotective agent,existing in the human body.Ergothioneine can be transferred inside mitochondria by the transporter OCTN-1 in skin keratinocytes and fibroblasts,thus playing the anti-oxidation and protection functions there.
EGT is accumulated into different cellular compartments via its specific transporter OCTN-1,abundantly expressed in mitochondrial DNA is especially vulnerable to stress because unlike nuclear DNA,there are no histones to protect mitochondrial DNA.Reactive oxygen species,like superoxides O2- generated in the mitochondria by respiration,are directly scavenged by EGT.EGT presents in the cytoplasm also scavenges a variety of ROS and reactive nitrogen species.EGT absorbs UV radiation and prevents DNA breaks and mutations.
| Name | Ergothioneine |
| Grade | cosmetic Grade |
| Appearance | white powder |
| Specification | 98% |
Function and Application
L-ergothioneine is a functional ingredient in skin care
Studies demonstrated that L-ergothioneine protects skin cells from UV-irradiation. Scientific data have also showed that L-
ergothioneine presented anti-inflammatory, antioxidant, photoprotective, antimicrobial, anti-tyrosinase, anti-elastase, and anti-collagenase activities. It can be utilized as ingredient to suppress the severity of inflammatory skin diseases (e.g., eczema, seborrheic dermatitis, and psoriasis), offer photoprotection to the skin, and correct Hyperpigmentation . L-ergothioneine isconsidered as one of the top botanical ingredients used in anti-aging creams currently on the market . It has been used as a "secret ingredient" by several high-end cosmetic brands.
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