Chemical Intermediate 99% Purity Nootropics Raw Gts-21 Powder CAS 148372-04-7 Gts-21

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Gts-21
• Sample: Available
• MOQ: 1kg
• Mf: C19h22cl2n2o2
• CAS: 148372-04-7
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

What is GTS-21?

GTS-21 dihydrochloride is a selective α7 nicotinic acetylcholine receptor agonist, has recently been established as a promising treatment for inflammation. Target: nAChRin vitro: GTS-21 is one of the most potent α7nAChR agonists, has been reported to attenuate pro-inflammatory cytokine production, improve outcomes in sepsis models, pancreatitis, and ischemia-reperfusion injury, and inhibit the production of endotoxin-induced TNF in lung tissue.

Product Name	99% Purity Nootropics Raw Gts-21 Powder CAS 148372-04-7 Gts-21
Appearance	White powder
Molecular formula	C19H20N2O2
Molecular Weight	308.37
Keywords	Raw Powder Gts-21;Gts-21 Powder;Gts-21 Nootropics
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

1. Nootropics also referred to as smart drugs, memory enhancers, neuro enhancers, cognitive enhancers, and intelligence enhancers, are drugs, supplements, nutraceuticals, and functional foods that purportedly improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration. Nootropics are thought to work by altering the availability of the brain's supply of neurochemicals (neurotransmitters, enzymes, andhormones), by improving the brain's oxygen supply, or by stimulating nerve growth.

1. GTS-21 has a high affinity for the rodent α7nAChR but its affinity for human α7nAChR is described to be low. Its metabolite, 4OH-(GTS-21) has been described to be a selective partial agonist with greater efficacy for both human and rat α7nAChRs (Conejero-Goldberg et al., 2008, Kem, 2000).
2. Both GTS-21 itself and its demethylated active metabolite 4-OH-GTS-21display nootropic[ and neuroprotective effects, and GTS-21 is being investigated for the treatment of Alzheimer's disease,nicotine dependence,and, most significantly, for schizophrenia 

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