Antineoplastic Terbinafine HCl Powder CAS 78628-80-5 Terbinafine Hydrochloride

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A23
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Name: Terbinafine Hydrochloride
• Appearance: White Powder
• Assay: 99%
• CAS: 78628-80-5
• OEM: Available
• Sample: Available
• Suitable: Adult
• Function: Antifungal Treatment
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Aspect	Details
Terbinafine Hydrochloride CAS Number	78628-80-5
Terbinafine Hydrochloride MF	C21H26ClN
Terbinafine Hydrochloride Molecular Weight	327.89
Terbinafine Hydrochloride  Grade	Pharm Grade
Terbinafine Hydrochloride Purity	99%
Terbinafine Hydrochloride Test Method	HPLC

Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.
Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.

 

1. Antifungal Treatment: Terbinafine Hydrochloride is primarily used in the treatment of fungal infections, particularly those affecting the skin, nails, and hair.
2. Dermatological Use: It is a popular choice for topical and oral administration in dermatological practice to combat ringworm, athlete's foot, jock itch, and other superficial fungal infections.
3. Nail Fungus Treatment: Effectively treats onychomycosis (fungal nail infections), which can be difficult to eradicate with other medications.
4. Tinea Infections: Used to manage a wide range of tinea infections, including tinea corporis (body ringworm), tinea cruris (jock itch), and tinea pedis (athlete's foot).

1. Inhibits Fungal Growth: Terbinafine functions by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. This disruption leads to fungal cell death.
2. Broad-Spectrum Antifungal Activity: It exhibits a broad spectrum of activity against dermatophytes, yeasts, and some molds, making it effective against a wide range of fungal pathogens.
3. Oral & Topical Formulations: Available in both oral and topical formulations, allowing for flexible treatment options based on the severity and location of the infection.
4. Minimal Systemic Absorption (Topical): Topical formulations have minimal systemic absorption, reducing the risk of side effects compared to oral administration, while still being effective at treating localized infections.
5. Highly Effective: Known for its high cure rates and low relapse rates, particularly in the treatment of nail fungal infections where traditional therapies often fall short.