Sodium Valproate Chemical Intermediate Antiepileptic CAS 1069-66-5 Sodium Valproate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Sodium Valproate
• Sample: Available
• MOQ: 1kg
• Mf: C8h15o2na
• CAS: 1069-66-5
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

Sodium valproate, with a chemical formula of C8H15O2Na and a molecular weight of 166.193, is a broad-spectrum antiepileptic supplement without nitrogen. This product has varying degrees of antagonism to convulsions caused by various methods. It is effective for various types of human epilepsy, such as various types of minor seizures, myoclonic epilepsy, localized seizures, major seizures and mixed epilepsy. Oral absorption is fast and complete, mainly distributed in the extracellular fluid, and most of it is combined with plasma proteins in the blood. 

Product Name	Sodium Valproate
CAS Number	1069-66-5
Molecular Formula	C8H15NaO2
Molecular Weight	166.193
Boiling Point	300 °C
Apperance	White powder
Application	Pharmaceuticals

1. Type 2 Diabetes Mellitus: Pioglitazone HCl is prescribed for the treatment of type 2 diabetes, particularly in patients who are not adequately controlled with diet and exercise alone or who are already on other oral antidiabetic medications.
2. Combination Therapy: It can be used in combination with other oral antidiabetic agents, such as sulfonylureas or metformin, to further enhance glycemic control.
3. Resistance: Pioglitazone HCl is also indicated for the improvement of sensitivity in patients with resistance, which may help in reducing the risk of cardiovascular complications associated with diabetes.

1. Sensitization: The primary function of Pioglitazone HCl is to increase sensitivity in target tissues, such as muscle, fat, and liver. This allows for better utilization of glucose by these tissues, thereby lowering blood glucose levels.
2. Reduction of Resistance: By activating peroxisome proliferator-activated receptor-gamma (PPAR-γ) in adipocytes, Pioglitazone HCl promotes adipocyte differentiation and reduces adipogenesis, which helps in alleviating resistance.
3. Cardiovascular Benefits: In addition to its glycemic effects, Pioglitazone HCl has been shown to have beneficial effects on the cardiovascular system, including improvements in endothelial function and reductions in inflammatory markers. However, its cardiovascular benefits should be weighed against potential risks, such as weight gain and fluid retention.

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