Factory 99% Amantadine HCl Powder CAS 665-66-7 Antiviral Chemical Intermediate Amantadine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A699
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Amantadine HCl
• CAS: 665-66-7
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Amantadine HCl
Appearance	White Powder
CAS NO.	665-66-7
MF	C10H18ClN
Storage	Keep in a cool, dry, dark location

 

Amantadine HCl is a versatile medication with applications in the treatment of Parkinson's disease, influenza A virus prophylaxis, and post-stroke syndrome. Its functions include dopamine modulation, viral M2 ion channel inhibition, and NMDA receptor antagonism, making it an effective therapeutic option for these conditions.

 

1. Parkinson's Disease: Amantadine HCl is primarily used in the treatment of Parkinson's disease, a neurodegenerative disorder characterized by muscle rigidity, tremors, and impaired balance. It helps to improve motor function and reduce symptoms by modulating dopamine levels and NMDA receptor activity.
2. Influenza A Virus Prophylaxis: Additionally, amantadine HCl is indicated for the prophylaxis of influenza A virus infections. By inhibiting the viral M2 ion channel, it prevents the virus from uncoating and replicating within host cells.
3. Post-Stroke Syndrome: In some cases, amantadine HCl may also be used to treat post-stroke syndrome, particularly when it involves hemiparesis (weakness on one side of the body), to improve motor function and mobility.

1. Dopamine Modulation: In Parkinson's disease, amantadine HCl is thought to increase dopamine levels in the brain by blocking its reuptake and enhancing its release, thereby alleviating motor symptoms.
2. Viral M2 Ion Channel Inhibition: Its antiviral activity against influenza A virus is attributed to the inhibition of the viral M2 ion channel, which is crucial for the virus's entry and replication within host cells. By blocking this channel, amantadine HCl prevents the virus from spreading and causing disease.
3. NMDA Receptor Antagonism: Amantadine HCl also acts as an NMDA receptor antagonist, which may contribute to its neuroprotective effects in conditions like Parkinson's disease and post-stroke syndrome. By reducing NMDA receptor-mediated excitotoxicity, it helps to protect neurons from damage and promote functional recovery.