Factory 99% Escitalopram Oxalate Powder CAS 219861-08-2 Chemical Intermediate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A827
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Escitalopram Oxalate
• CAS: 219861-08-2
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Escitalopram Oxalate
Appearance	White Powder
CAS NO.	219861-08-2
Storage	Keep in a cool, dry, dark location

 

Escitalopram Oxalate, also known as Escitalopram ((S)-Citalopram) oxalate, is the S-isomer of the racemic Citalopram. It is a selective serotonin reuptake inhibitor (SSRI) with a Ki value of 0.89 nM, exhibiting a 30-fold higher binding affinity compared to its R(-)-enantiomer.

 

1. Treatment of Depression: Escitalopram Oxalate is primarily used in the treatment of depression, particularly in cases of major depressive disorder (MDD) and generalized anxiety disorder (GAD).
2. Antidepressant Therapy: As an SSRI, it is prescribed to enhance serotonin neurotransmission in the central nervous system, thereby alleviating depressive symptoms.
3. Long-term Management: It can be used for long-term management of depressive conditions, offering sustained therapeutic benefits with good tolerability and minimal adverse effects.

1. Selective Serotonin Reuptake Inhibition: Escitalopram Oxalate selectively inhibits the reuptake of serotonin (5-HT) at the presynaptic membrane, thereby increasing synaptic serotonin levels and enhancing serotonergic neurotransmission.
2. Modulation of Mood and Anxiety: By enhancing serotonergic activity, it exerts antidepressant and anxiolytic effects, improving mood, reducing anxiety, and alleviating symptoms associated with depression and GAD.
3. Neuroprotective and Cardiovascular Benefits: In addition to its primary antidepressant action, Escitalopram Oxalate has also been shown to exhibit neuroprotective properties and may be beneficial in reducing platelet aggregation, protecting endothelial function, and mitigating inflammatory responses, potentially contributing to the prevention of atherosclerosis and stable plaque formation.