Factory 99% Metoclopramide HCl CAS 54143-57-6 Chemical Intermediate Metoclopramide HCl

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A403
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Metoclopramide HCl
• CAS: 54143-57-6
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 100g
• Function: Anti-Inflammatory
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Metoclopramide HCl
Appearance	White Powder
CAS NO.	54143-57-6
Molecular Formula	C14H25Cl2N3O3
Storage	Keep in a cool, dry, dark location

 

Metoclopramide HCl is an orally administered selective dopamine D2 receptor antagonist and 5-HT3 receptor antagonist, utilized primarily in the management of nausea and vomiting.

 

 

1. Anti-emetic Therapy: It is prescribed for the treatment of nausea and vomiting induced by various factors such as medications, uremia, and radiotherapy.
2. Gastroesophageal Reflux Disease (GERD): Metoclopramide HCl is used to alleviate symptoms associated with GERD by enhancing gastric emptying and reducing acid reflux.
3. Gastric Stasis and Gastroparesis: It improves gastrointestinal motility, aiding in the management of conditions like gastric stasis and gastroparesis.

1. Dopamine D2 Receptor Antagonism: By blocking dopamine D2 receptors in the chemoreceptor trigger zone and the vomiting center of the brain, Metoclopramide HCl inhibits the emetic reflex, thereby reducing nausea and vomiting.
2. 5-HT3 Receptor Antagonism: Its action as a 5-HT3 receptor antagonist further contributes to anti-emetic effects, modulating serotonin-mediated signaling involved in nausea and vomiting.
3. Gastrointestinal Motility Enhancement: By promoting the release of acetylcholine and inhibiting dopamine's inhibitory effect on gastrointestinal motility, Metoclopramide HCl enhances gastric and intestinal contractions, facilitating the movement of food through the digestive tract.