| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Chloroamphenicol |
| Appearance | White Powder |
| CAS NO. | 56-75-7 |
| Storage | Keep in a cool, dry, dark location |
Chloroamphenicol is a broad-spectrum antibiotic derived from Streptomyces venezuelae. It belongs to the phenicol class of antibiotics and is primarily used to treat serious bacterial infections that are resistant to other antibiotics. Due to its potential toxic effects, particularly on the bone marrow, its use is now restricted in many countries.
Treatment of Severe Infections: Chloroamphenicol is often prescribed for the treatment of severe bacterial infections such as meningitis, typhoid fever, and rickettsial infections when other antibiotics are ineffective or contraindicated.
Veterinary Use: In veterinary medicine, it is used to treat various bacterial infections in livestock and pets, although its use is also regulated due to potential side effects.
Topical Applications: Some formulations of chloroamphenicol are available for topical use, such as eye drops and ointments, to treat bacterial conjunctivitis and other superficial infections.
Bacterial Inhibition: Chloroamphenicol functions by inhibiting protein synthesis in bacteria. It specifically targets the 50S ribosomal subunit, preventing the formation of essential bacterial proteins and thus stopping bacterial growth and replication.
Broad-Spectrum Activity: It exhibits broad-spectrum antibacterial activity against both Gram-positive and Gram-negative bacteria, making it useful in treating a wide range of infections.
Intracellular Penetration: Chloroamphenicol can penetrate into cells, including macrophages, making it effective against intracellular bacteria that other antibiotics may struggle to reach.
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