Chemical Intermediate Ibrutinib Powder CAS 936563-96-1 Anti-Cancer Ibrutinib

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Ibrutinib
• Sample: Available
• MOQ: Consult
• Mf: C25h24n6o2
• CAS: 936563-96-1
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

 

Ibrutinib is an orally available, small-molecule inhibitor of Bruton's tyrosine kinase (BTK). It forms a covalent bond with the cysteine residue in the BTK active site, leading to irreversible inhibition of BTK activity.

 

Product Name	Ibrutinib
Appearance	White Powder
CAS NO.	936563-96-1
Molecular Formula	C25H24N6O2
Storage	Keep in a cool, dry, dark location

1. Inhibition of BTK Activity: By covalently binding to the BTK active site, ibrutinib irreversibly inhibits BTK activity, thereby blocking the B-cell receptor (BCR) signaling pathway.
2. Suppression of Tumor Cell Growth and Survival: Inhibition of BTK activity disrupts the survival and proliferation of malignant B cells, leading to tumor cell apoptosis and reduction in tumor burden.
3. Modulation of Immune Response: Ibrutinib also affects the immune system by inhibiting the function of various immune cells, which may contribute to its therapeutic effects in autoimmune diseases.

1. Oncological Treatment: Approved by the U.S. Food and Drug Administration (FDA) for the treatment of mantle cell lymphoma (MCL) and chronic lymphocytic leukemia (CLL). It is used as a monotherapy or in combination with other agents.
2. Research and Development: Utilized in preclinical and clinical research to investigate its therapeutic potential in various B-cell malignancies and autoimmune diseases.
3. Pharmaceutical Industry: Employed as a key active ingredient in the formulation of pharmaceutical products for the treatment of the aforementioned conditions.

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Xi'an Xinlu Biotechnology Co., Ltd. is a high-end brand company focusing on the biomedical industry and integrating R&D, production and sales.  It has an independent R&D center, advanced laboratory equipment and a professional R&D team, a GMP standard production workshop, a complete set of internationally advanced assembly line equipment, a preparation workshop with a cleanliness level of 100,000, as well as sophisticated testing instruments and scientific testing methods, providing solid technical support for the production of high-quality products.  Through long-term R&D, production, and sales practices, it has formed its own unique product line, providing users with products of reliable quality at highly affordable prices.  We strictly control quality, ensure the stability of product quality in all aspects, and win the trust of customers with high quality and high-level development.