Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Biktigravir (BIC) is a second-generation integrase chain transfer inhibitor (INSTI), which has been approved for use in fixed-dose combination with emtricitabine and tenofovir alafenamiChemicalbookde for HIV treatment. The first-generation resistant strains have effective antiviral activity INSTIs in vitro.
Product Name | Factory Supply 99% Bictegravir Powder CAS 1611493-60-7 Bictegravir |
Appearance | white powder |
CAS | 1611493-60-7 |
Assay | 99% |
Keywords | Bictegravir;Bictegravir Powder;Bictegravir CAS 1611493-60-7 |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
Biktigravir mainly clears the liver through cytochrome P4503A4 (CYP3A4) oxidation and UDP-glucosyltransferase 1A1 (UGT1A1) glucuronidation. Therefore, due to the significant reduction of Biktegravir blood Chemicalbook clear exposure, the use of potent inducers of UGT1A1 and CYP3A4 (such as rifamycin/anticonvulsants) should be avoided. Chelating with polyvalent cations can reduce absorption; otherwise, there is little interaction between the drug and the drug.
Bictegravir (BIC) is a new type of integrase inhibitor, a new research drug of integrase inhibitor discovered by scientists. As of June 2016, Bictegravir (BIC) was used as a single-tablet regimen in combination with Tenofovir Alafe Chemicalbooknamide Fumarate (TAF) and Emtricitabine (FTC) for the treatment of HIV-1 infection, BIC/ In the 48-week Phase III clinical trial of FTC/TAF, it was found that it has a high virus inhibition rate, which can inhibit 97% of the virus, and no adverse reactions have been found. It is less toxic to bone and kidney, and may become the most Competitive anti-HIV drugs.
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