| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Appearance | powder |
| cas | 30516-87-1 |
| Assay | 99% |
| Keywords | Raw Material Zidovudine;Zidovudine Powder;Hiv Zidovudine |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
Zidovudine is the world's first anti-AIDS drug approved by the US FDA. Because of its definite curative effect, it has become the most basic component of "cocktail" therapy. It is highly active against retroviruses including human immunodeficiency virus (HIV) in vitro.
In virus-infected cells, it is phosphorylated by cellular thymidine kinase to zidovudine triphosphate, which can selectively inhibit HIV reverse transcriptase, leading to the termination of HIV chain synthesis and preventing HIV replication.
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