| Customization: | Available |
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| Certification: | RoHS, BRC, ISO, FDA, HACCP |
| Assay Method: | HPLC-MS, GPC, HPLC, UV |
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| Product Name | Lappaconitine |
| Appearance | White Powder |
| CAS NO. | 32854-75-4 |
| Storage | Keep in a cool, dry, dark location |
Lappaconitine is a bioactive alkaloid isolated from the roots of plants belonging to the genus Aconitum, particularly Aconitum sinomontanum Nakai, which is native to China. It is also known as high wusine, lappaconitin, or simply as the active ingredient in high wusine. Lappaconitine exhibits unique pharmacological properties due to its ability to interact with sodium ion channels and neurotransmitter systems.
Analgesic Agent: Lappaconitine is primarily used as an analgesic agent due to its potent pain-relieving properties. It is employed in the treatment of various types of pain, including chronic pain conditions.
Pharmaceutical Ingredient: In the pharmaceutical industry, lappaconitine is a key ingredient in the formulation of analgesic medications. It is often combined with other active ingredients to enhance the overall efficacy of pain relief treatments.
Research Tool: Due to its unique mechanism of action, lappaconitine is also used as a research tool in the study of pain perception and neurotransmitter function. It helps scientists understand the physiological processes underlying pain and develop new therapeutic strategies.
Sodium Channel Blocker: Lappaconitine functions as a sodium channel blocker, inhibiting the influx of sodium ions into nerve cells. This action disrupts the propagation of nerve impulses, reducing the transmission of pain signals to the brain.
Neurotransmitter Modulation: In addition to its sodium channel blocking activity, lappaconitine also modulates the release and uptake of neurotransmitters such as norepinephrine and serotonin. This neuromodulatory effect contributes to its analgesic properties by altering pain perception and emotional responses to pain.
Anti-Inflammatory Activity: Recent studies suggest that lappaconitine may also possess anti-inflammatory properties. By reducing inflammation, it can further alleviate pain and improve the overall health of affected tissues.
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