| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product name | Donepezil HCl |
| Appearance | white Powder |
| Specification | 99% |
| Shelf life | 2 years when properly stored |
Function and Application
Donepezil Hydrochloride improves the function of nerve cells in the brain. It works by preventing the breakdown of a chemical called acetylcholine (ah SEET il KOE leen). People with dementia usually have lower levels of this chemical, which is important for the processes of memory, thinking, and reasoning.Donepezil is used to treat mild to moderate dementia caused by Alzheimer's disease.
1. Mild or moderate Alzheimer-type dementia treatment.
Donepezil hydrochloride is a long-acting Alzheimer's disease (AD) in the symptomatic treatment drugs. AD is a kind of memory loss as the main performance, accompanied by other cognitive impairment of acquired intelligence decline.
2. Donepezil hydrochloride is a second-generation cholinesterase (CHE) inhibitor, its therapeutic effect is reversibly inhibiting acid hydrolysis of acetylcholine acetylcholinesterase (ACHE) caused by increased content of acetylcholine receptor sites.
3. Donepezil may have other mechanisms, including the disposal of the direct effect of the peptide, neurotransmitter receptors.
4.Donepezil hydrochloride selection of AchE affinity than to butyrylcholinesterase (BCHE) 1250 times stronger, it can inhibit the brain tissue CHE, but on the heart (myocardium) or small intestine (smooth) had no effect, probably on the chest organization (rhabdomyosarcoma) role; on the central nervous toxicity than tacrine.
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