Factory 98% Celastrol Powder Tripterygium Extract CAS 34157-83-0 Tripterine Celastrol

• Customization: Available
• Certification: RoHS, BRC, ISO, FDA, HACCP
• Assay Method: HPLC-MS, GPC, HPLC, UV
• Model NO.: C71
• Application Form: Injection, Lotion, Suppository, Paste, Tablet, Capsule
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Tripterygium Extract
• Name: Celastrol
• Appearance: Red Powder
• Assay: 98%
• CAS: 34157-83-0
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 10g
• Transport Package: Foil Bag
• Specification: 98
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Celastrol
Appearance	Red Powder
CAS NO.	34157-83-0
Storage	Keep in a cool, dry, dark location

 

Celastrol, also known as tripterine or tripterin, is a naturally occurring pentacyclic triterpenoid compound isolated from the root bark of the Chinese medicinal plant Tripterygium wilfordii, commonly known as thunder god vine. It belongs to the class of cembranoids and possesses a complex chemical structure with a molecular formula of C29H38O4 and a molecular weight of 450.61.

 

1. Cancer Research and Treatment: Celastrol is being studied extensively for its potential anticancer properties. It is known to induce apoptosis, inhibit cell proliferation, and disrupt tumor angiogenesis, making it a promising candidate for cancer therapy.
2. Inflammation and Autoimmune Diseases: Due to its potent anti-inflammatory and immunomodulatory effects, celastrol is being explored for the treatment of autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease.
3. Biomarker and Drug Development: Celastrol is used as a molecular probe in biological research to understand cellular pathways and signaling mechanisms. It is also being developed into derivative drugs with improved efficacy and reduced toxicity.

1. Anticancer Activity: Celastrol exhibits potent anti-proliferative and pro-apoptotic effects on various cancer cell lines. It targets multiple signaling pathways involved in cancer progression, including NF-κB, PI3K/Akt, and MAPK pathways.
2. Anti-inflammatory and Immunomodulatory Effects: Celastrol suppresses the production of inflammatory cytokines and chemokines, thereby reducing inflammation. It also regulates immune cell function, making it effective in treating autoimmune disorders.
3. Neuroprotective and Metabolic Benefits: Celastrol has shown neuroprotective effects in animal models of neurodegenerative diseases such as Alzheimer's disease. Additionally, it improves metabolic parameters by enhancing sensitivity and reducing fat accumulation.