| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Nitrofurantoin |
| Appearance | Yellow Powder |
| CAS NO. | 67-20-9 |
| Storage | Keep in a cool, dry, dark location |
Nitrofurantoin is an antibacterial agent that belongs to the nitrofuran class of antibiotics. It is commonly prescribed for the treatment of uncomplicated urinary tract infections (UTIs), particularly those caused by susceptible strains of Escherichia coli and other Gram-negative bacteria.
Urinary Tract Infections (UTIs): Nitrofurantoin is primarily used to treat lower UTIs, such as cystitis (bladder inflammation), in both adults and children. Its effectiveness is due to its high concentration in urine, which helps to eliminate the bacteria causing the infection.
Prophylaxis: In some cases, nitrofurantoin may be used as a prophylactic agent to prevent recurrent UTIs, especially in individuals who experience frequent infections. This long-term, low-dose use can help reduce the frequency of infections.
Specific Bacterial Infections: Beyond UTIs, nitrofurantoin may also be used to treat certain other bacterial infections, although its primary application remains in the management of urinary tract infections.
Bactericidal Activity: Nitrofurantoin exerts its antibacterial effect by inhibiting the synthesis of essential bacterial proteins and DNA, leading to bacterial cell death. This bactericidal action is crucial for clearing the infection.
Broad Spectrum of Activity: While nitrofurantoin is particularly effective against E. coli and other Gram-negative bacteria commonly found in the urinary tract, it also has activity against some Gram-positive bacteria. This broad spectrum of activity enhances its usefulness in treating a variety of UTIs.
Safety and Tolerability: Nitrofurantoin is generally well-tolerated, with a low incidence of serious side effects. It is often preferred for use in pregnant women and individuals with renal impairment, as it is excreted primarily in the urine and poses minimal risk to systemic organs.
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