Factory Antispasmodic 99% Baclofen Powder CAS 1134-47-0 Baclofen

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A79
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Name: Baclofen
• Appearance: White Powder
• Assay: 99%
• CAS: 1134-47-0
• OEM: Available
• Sample: Available
• Suitable: Adult
• Function: Antispasmodic
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Baclofen
Appearance	White Powder
CAS NO.	1134-47-0
Molecular Formula	C10H12ClNO2
Storage	Keep in a cool, dry, dark location

 

Baclofen is a γ-aminobutyric acid derivative. It is an antispasmodics class drugs acting on the central nervous system, the brain and spinal cord as a skeletal muscle relaxants and sedatives. It take antispasmodic effect by stimulating receptors to inhibit the release of excitatory amino acids such as glutamic acid, aspartic acid and thereby inhibiting the transfer of single and multi-synaptic reflex in central nervous system, brain and spinal cord.

 

1. Spasticity Management: It is primarily used to alleviate muscle spasticity caused by various conditions such as cerebral palsy, multiple sclerosis, and spinal cord injuries.
2. Intrathecal Pump Therapy: In severe cases, baclofen can be administered intrathecally via an implanted pump, providing more targeted and sustained relief from spasticity.
3. Off-label Uses: Although not FDA-approved, baclofen has been explored for off-label uses like treating alcohol dependence, addiction recovery, and certain psychiatric conditions due to its potential effects on neurotransmitters.

1. GABA-Mimetic Action: Baclofen acts as a GABA-B receptor agonist, enhancing the inhibitory effects of GABA (gamma-aminobutyric acid), a neurotransmitter that decreases neural activity.
2. Decreasing Muscle Tone: By stimulating GABA-B receptors in the spinal cord and brain, baclofen reduces muscle overactivity and hypertonia, allowing for improved movement and decreased pain associated with spasticity.
3. Modulating Neurotransmission: It modulates the balance between excitatory and inhibitory neurotransmitters, contributing to its therapeutic effects in managing neurological disorders and potential psychotropic benefits in off-label applications.