Aprepitant Powder Pharmaceutical Intermediates CAS 170729-80-3 99% Aprepitant

• Customization: Available
• Powder: Yes
• Customized: Customized
• Certification: ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >96%
• MOQ: 1kg
• Key Word: Aprepitant
• Key Word 1: CAS 170729-80-3
• Transport Package: 1kg Foil Bag
• Specification: 99%
• Trademark: /
• Origin: China
• Production Capacity: 1000t

Product Description

Description

Aprepitant is a neurokinin-1 (NK-1) receptor antagonist, belonging to anti-cancer chemotherapeutic vomiting drugs.  This product has a highly selective affinity for humans, but has a low affinity for 5-hydroxytryptamine, dopamine and corticosteroid receptors.  Aprepitant in combination with 5-HT3 receptor inhibitors (e.g., ondansetron hydrochloride) may further reduce acute and/or delayed cisplatin induced vomiting.  Single use of this drug has a certain preventive effect.

Product Name	Aprepitant	Appearance	white powder
Cas No.	170729-80-3	Shelf life	2 years

Function and Application
Aprepitant is an antiemetic chemical compound that belongs to a class of drugs called substance P antagonists.   Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of highly emetogenic cancer chemotherapy.   Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors.   Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting (CI NV).