Customization: | Available |
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Certification: | ISO, FDA |
Assay Method: | HPLC |
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Name | Superoxide Dismutase |
CAS No | 9054-89-1 |
Appearance | light yellow powder |
Specification | 20000/10000iu |
Function
Food Industry:
SOD content is higher in vegetables and fruits, such as bananas, hawthorn, prickly pear, kiwi, garlic, etc.,
and other such as scallops, chicken, etc. The activity of SOD is higher in the peel than in the flesh, and in fresh fruit is higher
than the fruit after being placed. It is processed into health products and food additives in various forms, such as milk,
beer, soft candy and other types of food nutrition fortifiers with SOD added.
Daily chemical industry:
Skin aging and damage are important characteristics of human aging, and human aging is a consequence of obstacles
aused by accumulation or removal of reactive oxygen species free radicals. Excess free radicals in the body can cause cell
damage and pigmentation. Since the human skin is in direct contact with oxygen, it will cause skin aging and damage. The
supplementation of exogenous SOD is beneficial to delay skin aging, anti-oxidation and discoloration. Therefore, many
cosmetics manufacturers at home and abroad have added a certain percentage of SOD to their products.
Anti-inflammatory:
Because SOD is a specific disproportionation catalyst that acts on superoxide anion free radicals, SOD, as a pharmaceutical
product, has a significant effect in treating inflammation, autoimmunity, and cardiovascular and cerebrovascular diseases
caused by free radicals. SOD can use its antioxidant effects to inhibit inflammation types such as arthritis, pleurisy, and acute
bronchitis.
Anti-tumor aspects:
In the human body, SOD can effectively eliminate cancer cells by eliminating superoxide anion radicals, and the expression
effect of Mn-SOD is more prominent.
Application
Activity
Superoxide dismutase has powerful antinflammatory activity. For example, SOD is a highly effective experimental treatment of chronic inflammation in colitis. Treatment with SOD decreases reactive oxygen species generation and oxidative stress and, thus, inhibits endothelial activation and indicate that modulation of factors that govern adhesion molecule expression and leukocyte-endothelial interactions. Therefore, such antioxidants may be important new therapies for the treatment of inflammatory bowel disease.
Cosmetic uses
Superoxide dismutase may reduce free radical damage to skin-for example, to reduce fibrosis following radiation for breast cancer. Studies of this kind must be regarded as tentative, however, as there were not adequate controls in the study including a lack of randomization, double-blinding, or placebo. Superoxide dismutase is known to reverse fibrosis, perhaps through reversion of myofibroblasts back to fibroblasts.
Commercial sources
Superoxide dismutase is commercially obtained from bovine liver, horseradish, cantaloupe and by fermenting certain bacteria, though it is found in most living forms at diverse concentrations. For therapeutic purpose, SOD is usually injected locally. There is no evidence that ingestion of unprotected SOD or SOD-rich foods can have any physiological effects: as all ingested SOD is broken down into amino acids before being absorbed. However, ingestion of SOD bound to wheat proteins could improve its therapeutic activity, at least in theory.