99% Rapamycin Powder CAS 53123-88-9 Factory Antineoplastic Rapamycin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A137
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Name: Rapamycin
• Appearance: White Powder
• Assay: 99%
• CAS: 53123-88-9
• OEM: Available
• Sample: Available
• Suitable: Adult
• Function: Antineoplastic
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Rapamycin
Appearance	White Powder
CAS NO.	53123-88-9
Molecular Formula	C51H79NO13
Storage	Keep in a cool, dry, dark location

 

Rapamycin, also known as Sirolimus, is a macrolide antibiotic and immunosuppressant derived from the bacterium Streptomyces hygroscopicus. It belongs to the class of mTOR (mammalian target of rapamycin) inhibitors, which play a critical role in regulating cell growth, proliferation, and metabolism.

 

 

1. Immunosuppression: Rapamycin is used as an immunosuppressive agent to prevent organ rejection in transplant patients. It helps to reduce the risk of rejection by suppressing the immune system's response to the transplanted organ.
2. Cancer Treatment: There is ongoing research exploring the potential use of rapamycin and its derivatives in cancer therapy. It has shown promise in inhibiting tumor growth and inducing autophagy (a cellular process of self-degradation) in cancer cells.
3. Research Tool: Due to its ability to modulate the mTOR pathway, rapamycin is also widely used as a research tool to study cell growth, proliferation, and aging.

1. mTOR Inhibition: The primary function of rapamycin is to inhibit the mTOR pathway, a key signaling pathway involved in cell growth, division, and metabolism. By blocking mTOR, rapamycin can slow down or stop cell proliferation, which is important for its immunosuppressive and anticancer effects.
2. Immunomodulation: Rapamycin modulates the immune system by inhibiting the activation and proliferation of T-cells, a type of white blood cell that plays a central role in immune responses. This immunosuppressive effect is crucial for preventing organ rejection in transplant patients.
3. Autophagy Induction: In addition to inhibiting mTOR, rapamycin can also induce autophagy, a cellular process that involves the degradation and recycling of damaged or unnecessary cellular components. This process is thought to play a role in maintaining cellular health and preventing disease.