| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name | Parecoxib Sodium |
| CAS NO. | 198470-85-8 |
| Purity | 99% |
| Melting Point | 273-275 C |
| Appearance and shape | White powder |
Parecoxib is a water soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral medications.
Postoperative Pain Management: Administered following surgical procedures to provide effective pain relief and reduce the need for opioids, thereby minimizing potential side effects associated with those medications.
Acute Pain Management: Used in the management of acute pain conditions, such as dental procedures, sports injuries, or acute exacerbations of chronic pain, where a rapid onset of analgesia is desired.
Reduction of Inflammation: By inhibiting the production of prostaglandins, parecoxib sodium helps reduce inflammation and associated swelling, discomfort, and stiffness, particularly in conditions where inflammation is a significant component of the pain experience.
COX-2 Inhibition: Acts as a selective inhibitor of cyclooxygenase-2 (COX-2) enzyme, an enzyme involved in the synthesis of prostaglandins that mediate pain, inflammation, and fever. By targeting COX-2 specifically, parecoxib reduces these symptoms with fewer gastrointestinal side effects compared to non-selective NSAIDs.
Analgesic Effect: Provides analgesic (pain-relieving) effects by blocking the conversion of arachidonic acid to prostaglandins, reducing the sensitization of pain receptors and inhibiting the transmission of pain signals to the brain.
Anti-inflammatory Action: Suppresses the inflammatory response by inhibiting the production of inflammatory prostaglandins and cytokines, thereby reducing swelling, redness, warmth, and pain at the site of injury or inflammation.
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