| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
Still deciding? Get samples of US$ 240/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
| Product name | Lamivudine |
| Cas number | 134678-17-4 |
| Apperance | White powder |
| MF | C8H11N3O3S |
| MW | 229.26 |
Lamivudine is (-)-2',3'-dideoxy-3'-thiacytidine, (-)-β-L-(2R,5S)-1,3-oxathiolanylcytosine, 3TC, or (-)-(S)-ddC.Lamivudine is a synthetic nucleoside analog that differsfrom 2β,3β-dideoxycytidine (ddC) by the substitution of asulfur atom in place of a methylene group at the 3'-positionof the ribose ring. In early clinical trials, lamivudine exhibitedhighly promising antiretroviral activity against HIVand low toxicity in the dosages studied.
Treatment of Chronic Hepatitis B: Lamivudine is primarily used as a therapeutic agent in the management of chronic hepatitis B virus (HBV) infection. It helps to reduce viral load and improve liver function in patients with chronic HBV.
Prevention of Post-Transplant Hepatitis B Recurrence: In individuals undergoing liver transplantation due to HBV-related liver disease, lamivudine is often prescribed to prevent the recurrence of hepatitis B post-surgery.
Combination Therapy: It is frequently combined with other antiviral medications, such as adefovir or tenofovir, to enhance the efficacy of treatment and reduce the risk of resistance development against a single agent.
Inhibits HBV Replication: Lamivudine functions by inhibiting the reverse transcriptase enzyme of the hepatitis B virus. This enzyme is essential for the virus to replicate its genetic material, thus blocking its ability to propagate within the infected cells.
Decreases Viral Load: By inhibiting viral replication, lamivudine helps to significantly decrease the amount of virus (viral load) in the bloodstream and liver, which can alleviate disease symptoms and prevent disease progression.
Improves Liver Function: By reducing viral load, lamivudine can also improve liver function and slow down or reverse liver damage caused by chronic hepatitis B infection, potentially delaying the need for liver transplantation in some patients.
){kind=link}