Factory 99% Idarubicin HCl Powder CAS 57852-57-0 Chemical Intermediate Idarubicin HCl

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A869
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Idarubicin HCl
• CAS: 57852-57-0
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Idarubicin HCl
Appearance	White Powder
CAS NO.	57852-57-0
Storage	Keep in a cool, dry, dark location

 

Idarubicin HCl is a potent antineoplastic agent belonging to the anthracycline class of drugs. It is a chemical compound with the molecular formula C26H28ClNO9 and a molecular weight of approximately 533.955 g/mol. As the hydrochloride salt of idarubicin, it is water-soluble and commonly used in clinical settings for cancer treatment.

 

1. Cancer Chemotherapy: Idarubicin HCl is primarily used in the treatment of various types of cancer, including acute myeloid leukemia (AML), acute lymphocytic leukemia (ALL), and some solid tumors.
2. Combination Therapy: It is often administered in combination with other chemotherapeutic agents to enhance the treatment effect and reduce the risk of drug resistance.
3. Off-label Uses: Although not approved for these purposes, Idarubicin HCl may also be used off-label for the treatment of other conditions, such as multiple myeloma and non-Hodgkin's lymphoma, based on the discretion of the treating physician.

1. Inhibition of DNA Synthesis: Idarubicin HCl functions by inhibiting the activity of DNA topoisomerase II, an enzyme involved in DNA replication and transcription. This inhibition leads to DNA strand breaks and ultimately cell death.
2. Induction of Apoptosis: By enhancing the expression of Fas and caspase-3/caspase-7, Idarubicin HCl triggers the apoptotic pathway in cancer cells, promoting programmed cell death.
3. Antitumor Activity: It exhibits broad-spectrum antitumor activity against a variety of cancer cell lines, making it a valuable addition to the armamentarium of cancer chemotherapy.