Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Amiodarone HCl |
Appearance | White Powder |
CAS NO. | 19774-82-4 |
MF | C25H29I2NO3·HCl |
Storage | Keep in a cool, dry, dark location |
Amiodarone HCl is a versatile antiarrhythmic agent with a wide range of applications in cardiac arrhythmia management. Its multifaceted mechanism of action, including channel blocking, beta-blocking, and calcium channel blocking effects, combined with its antioxidant and anti-inflammatory properties, make it a valuable tool in the treatment of various cardiovascular conditions.
Cardiac Arrhythmia Management: Amiodarone HCl is primarily used in the management of various cardiac arrhythmias, including atrial fibrillation, atrial flutter, and ventricular tachycardia. Its broad-spectrum efficacy makes it a valuable option in complex or refractory cases.
Preoperative and Postoperative Care: In patients undergoing heart surgery, amiodarone HCl can be used to prevent or treat postoperative atrial fibrillation, reducing the risk of complications and improving patient outcomes.
Critical Care Settings: In critical care units, amiodarone HCl is often administered for the treatment of life-threatening arrhythmias, where its efficacy and safety profile make it a suitable choice for emergency situations.
Blocking Sodium and Potassium Channels: Amiodarone HCl blocks sodium and potassium channels in the heart, thereby prolonging the action potential duration and refractory period. This action helps to stabilize the cardiac electrical activity and reduce the likelihood of arrhythmias.
Beta-Blocking and Calcium Channel Blocking Effects: In addition to its primary channel-blocking action, amiodarone HCl also exhibits beta-blocking and calcium channel blocking properties. These effects contribute to its antiarrhythmic activity by reducing heart rate and contractility.
Antioxidant and Anti-inflammatory Properties: Amiodarone HCl possesses antioxidant and anti-inflammatory properties that may help protect the heart from ischemia-reperfusion injury and reduce inflammation associated with cardiac diseases.