Factory 99% Triamterene Powder CAS 396-01-0 Chemical Intermediate Triamterene

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A928
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Triamterene
• CAS: 396-01-0
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 1g
• Function: Chemical Intermediate
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

 

Product Name	Triamterene
Appearance	White Powder
CAS NO.	396-01-0
Storage	Keep in a cool, dry, dark location

 

Triamterene is a medication that belongs to the class of potassium-sparing diuretics, specifically acting as a blocker of the pressure-sensitive epithelial sodium channel (ENaC).

 

1. Edema Management: Triamterene is used to treat edema (fluid retention) caused by various conditions, such as heart failure, liver cirrhosis, and chronic kidney disease. It helps to reduce excess fluid in the body by increasing urine output.

2. Adjuvant Therapy: It is often used in combination with other diuretics, particularly loop diuretics like furosemide, to enhance diuretic efficacy while minimizing potassium loss. This combination therapy is particularly beneficial in patients who are at risk of developing hypokalemia (low potassium levels).

3. Hypertension Treatment: Triamterene may also be prescribed to treat hypertension (high blood pressure), especially when combined with other antihypertensive medications.

1. Sodium Channel Blockade: Triamterene blocks the ENaC in the distal nephron of the kidney, reducing the reabsorption of sodium and chloride ions from the urine. This leads to increased excretion of these ions and, consequently, increased urine volume.

2. Potassium Retention: Unlike some other diuretics, triamterene does not promote potassium excretion. In fact, it can help retain potassium in the body, making it a useful choice for patients who are at risk of hypokalemia.

3. Vasodilatory Effects: In addition to its diuretic effects, triamterene may also have some vasodilatory properties, which can contribute to its antihypertensive effects. However, this aspect of its function is less well-documented compared to its primary diuretic and potassium-sparing actions.