Factory Local Anesthetics Algesia Celecoxib Powder CAS 169590-42-5 Celecoxib

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A47
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Name: Celecoxib
• Appearance: White Powder
• Assay: 99%
• CAS: 69590-42-5
• OEM: Available
• Sample: Available
• Suitable: Adult
• Function: Local Anesthetics Algesia
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Celecoxib
CAS NO.	169590-42-5
Purity	99%
Density	1.43
Appearance and shape	White powder

 

Celecoxib is a selective Cox-2(cyclooxygenase-2) inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LMP1 (IC50 of 61.31 μM).
Celecoxib is a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). It is used to treat the pain and inflammation of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain in adults, painful menstruation, and juvenile rheumatoid arthritis in people.

 

1. Osteoarthritis and Rheumatoid Arthritis: Celecoxib is primarily used for the relief of pain, inflammation, and stiffness caused by osteoarthritis and rheumatoid arthritis.

2. Acute Pain Management: It can also be prescribed for the short-term management of acute pain in adults, such as post-operative pain or pain from injuries.

3. Dysmenorrhea (Painful Menstrual Cramps): Celecoxib has been found to be effective in reducing the pain and discomfort associated with menstrual cramps.

1. Selective COX-2 Inhibitor: Celecoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which is responsible for the production of prostaglandins involved in pain, inflammation, and fever. This selectivity reduces the risk of gastrointestinal side effects compared to non-selective NSAIDs.

2. Anti-Inflammatory Action: By inhibiting COX-2, celecoxib reduces inflammation at the site of injury or disease, helping to alleviate pain and swelling.

3. Analgesic Effect: Its ability to inhibit prostaglandin production also contributes to its analgesic (pain-relieving) properties, allowing patients to manage their pain more effectively.