High Purity Chemical Intermediate Antiulcer Betahistine HCl Powder CAS 5579-84-0 Betahistine Dihydrochloride

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: API
• Certification: GMP, ISO 9001
• Suitable for: All
• State: Solid
• Purity: >99%
• Keyword: Betahistine HCl
• Sample: Available
• MOQ: 1kg
• Mf: C8h14cl2n2
• CAS: 5579-84-0
• Test Method: HPLC
• Transport Package: Aluminum Foil Bag/Paper Drum
• Specification: 99%
• Trademark: xinlu
• Origin: China
• Production Capacity: 100kg

Product Description

Betahistine HCl is a derivative of histamine. It is chemically 2-(2-aminoethyl) dihydrochloride. Its chemical structure is based on a  ring with an aminoethyl side chain, and it exists in the form of hydrochloride salt to improve its solubility and stability in aqueous solutions and pharmaceutical formulations.

Product Name	High Purity Pharmaceutical Antiulcer Betahistine HCl Powder CAS 5579-84-0 Betahistine Dihydrochloride
Appearance	powder
cas	5579-84-0
Assay	99%
Keywords	Betahistine Dihydrochloride Powder;Pharmaceutical Antiulcer Betahistine HCl;Betahistine HCl
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

1. Vasodilatory Action: Betahistine HCl selectively dilates blood vessels in the inner ear and brain. It acts on histamine H1 receptors in blood vessel walls, causing relaxation of smooth muscle cells in the blood vessel walls, thereby increasing blood flow to the inner ear and brain. This is particularly beneficial for improving blood supply to the vestibular system in the inner ear, which is crucial for maintaining balance and spatial orientation.
2. Reduction of Endolymphatic Pressure: It helps regulate the production and absorption of endolymph in the inner ear. By doing so, it can reduce the pressure in the endolymphatic system, which is often elevated in certain inner ear disorders. This pressure reduction can alleviate symptoms such as vertigo, tinnitus, and hearing loss that are associated with abnormal endolymphatic pressure.
3. Antagonism of Histamine H3 Receptors: In addition to its effects on H1 receptors, betahistine HCl also acts as an antagonist at histamine H3 receptors. This action modulates the release and activity of histamine and other neurotransmitters in the central nervous system, contributing to its overall therapeutic effects on balance and vestibular function.

1. Meniere's Disease: It is a first-line treatment for Meniere's disease, a disorder characterized by recurrent episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. Betahistine HCl helps relieve the symptoms of Meniere's disease by improving inner ear blood flow and reducing endolymphatic pressure, thereby reducing the frequency and severity of vertigo attacks and improving hearing function.
2. Vertigo of Various Etiologies: It is also used to treat vertigo caused by other factors, such as vestibular neuritis, benign paroxysmal positional vertigo (BPPV), and post-traumatic vertigo. By enhancing blood supply to the inner ear and regulating vestibular function, it helps patients recover balance and reduce vertigo symptoms, facilitating their rehabilitation and improving their quality of life.
3. Cerebral Circulation Disorders: In some cases, betahistine HCl is used to treat cerebral circulation disorders, such as transient ischemic attacks and chronic cerebral ischemia. By dilating blood vessels in the brain, it can improve cerebral blood flow, enhance oxygen and nutrient supply to brain tissues, and help alleviate symptoms such as dizziness, headache, and memory loss associated with poor cerebral circulation.

Pro-xylane	Potassium azeloyl diglycinate
Ghk-Cu or other Cosmetic peptides	Glutathione
Spermidine	5-deazaflavin
PQQ	Coenzyme Q10
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