Factory 99% Decitabine Powder CAS 2353-33-5 Anti-Tumor Decitabine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A307
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Powder
• Purity: >99%
• Name: Decitabine
• CAS: 2353-33-5
• Appearance: White Powder
• Assay: 99%
• OEM: Available
• Sample: Available
• Suitable: Adult
• MOQ: 100g
• Function: Anti-Tumor
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Decitabine
Appearance	White Powder
CAS NO.	2353-33-5
Molecular Formula	C8H12N4O4
Storage	Keep in a cool, dry, dark location

 

Decitabine is a synthetic pyrimidine analog that possesses potent antitumor activity. It acts as a DNA methyltransferase inhibitor, disrupting the DNA methylation process and affecting gene expression.

 

 

1. Treatment of Hematological Malignancies: Decitabine is primarily used in the treatment of hematological malignancies such as acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), and chronic myelogenous leukemia (CML).
2. Combination Therapy: It can be used in combination with other chemotherapeutic agents to enhance the therapeutic effect and potentially reduce drug resistance.
3. Epigenetic Therapy: As an epigenetic modifier, Decitabine is also being explored in the treatment of other solid tumors and non-hematological malignancies.

1. DNA Methylation Inhibition: Decitabine inhibits DNA methyltransferase enzymes, leading to hypomethylation of DNA and the reactivation of silenced tumor suppressor genes.
2. Cell Cycle Arrest and Apoptosis: By altering DNA methylation patterns, Decitabine can cause cell cycle arrest and induce apoptosis (programmed cell death) in cancer cells.
3. Immunomodulatory Effects: In addition to its direct antitumor effects, Decitabine may also modulate the immune system, enhancing the antitumor response of the host.