Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product Name | Itraconazole |
Appearance | White Powder |
CAS NO. | 84625-61-6 |
Molecular Formula | C35H38Cl2N8O4 |
Storage | Keep in a cool, dry, dark location |
Antifungal Treatment: Itraconazole is primarily used for the treatment of various fungal infections, including but not limited to systemic mycoses, dermatomycoses, and onychomycosis.
Immunocompromised Patients: It is prescribed for immunocompromised individuals, such as those with HIV/AIDS or undergoing chemotherapy, who are more susceptible to fungal infections.
Preventive Therapy: Itraconazole can also be employed as a prophylactic agent to prevent fungal infections in high-risk individuals or in settings where exposure to fungi is anticipated.
Inhibition of Fungal Cell Membrane Synthesis: By inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, itraconazole disrupts membrane integrity and function, leading to fungal cell death.
Broad-Spectrum Activity: Its mechanism of action enables itraconazole to exhibit broad-spectrum antifungal activity against a wide range of fungal species, including yeasts, molds, and dermatophytes.
Oral Bioavailability: Administered orally, itraconazole achieves good bioavailability, allowing it to reach therapeutic concentrations in the bloodstream and distribute throughout the body, making it effective against systemic and deep-seated fungal infections.