99% Promethazine HCl Powder CAS 58-33-3 Factory Antiemetic Promethazine Hydrochloride

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: A150
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Name: Promethazine HCl
• Appearance: White Powder
• Assay: 99%
• CAS: 58-33-3
• OEM: Available
• Sample: Available
• Suitable: Adult
• Function: Antiemetic
• MOQ: 10g
• Transport Package: Foil Bag
• Specification: 99
• Trademark: /
• Origin: China
• Production Capacity: 10000 Kgs Per Month

Product Description

Product Name	Promethazine HCl
Appearance	White Powder
CAS NO.	58-33-3
Molecular Formula	C17H20N2S·HCl
Storage	Keep in a cool, dry, dark location

 

Promethazine HCl, also known as promethazine hydrochloride, is a medication belonging to the class of phenothiazine derivatives. It is an antihistamine and sedative with additional anticholinergic and antiemetic properties.

 

 

1. Allergy Relief: Promethazine HCl is used to treat allergic symptoms such as itching, rash, and hives, by blocking histamine receptors in the body.
2. Nausea and Vomiting: It is prescribed for the prevention and treatment of nausea and vomiting caused by various conditions, including motion sickness, postoperative nausea, and chemotherapy-induced nausea and vomiting.
3. Sedation and Anxiolysis: Due to its sedative and anxiolytic effects, promethazine HCl is also employed for the management of anxiety, agitation, and to induce sleep in patients requiring sedation.

1. Antihistaminic Action: Promethazine HCl functions by competitively blocking histamine H1 receptors, thereby inhibiting the effects of histamine on target tissues, such as reducing allergic reactions and inflammation.
2. Sedative and Anticholinergic Effects: It exerts sedative effects by altering neurotransmitter levels in the brain, particularly by affecting the dopamine and serotonin systems. Additionally, its anticholinergic properties contribute to the reduction of gastrointestinal motility and secretions.
3. Antiemetic Properties: By blocking histamine receptors in the chemoreceptor trigger zone of the brain, promethazine HCl prevents nausea and vomiting, making it useful in the management of various conditions associated with these symptoms.